| TRACK A Basic Sciences
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A.1 |
Sexual transmission of HIV: New findings |
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A.2 |
Innate and adaptive immunity: Role in HIV mucosal
acquisition and control |
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A.3 |
Latest developments in biomarkers and in vitro models of
efficacy and safety |
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A.4 |
Animal models: Current status and latest data |
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A.5 |
Emerging microbicide candidates |
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A.6 |
Biological role of STIs in HIV transmission |
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A.7 |
Formulation and delivery strategies |
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| TRACK B Clinical |
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B.1 |
Empirical findings of Phase I and II
clinical trials of new microbicide products including rectal microbicides |
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B.2 |
Adherence and compliance to trial
procedures and product use: measurement, strategies, impact on retention
and recruitment |
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B.3 |
Effectiveness trial status and presentation
of baseline participant data |
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B.4 |
Alternative microbicide strategies and the role of
STIs in HIV prevention |
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B.5 |
Barrier method strategies |
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B.6 |
Testing methods/ algorithsm for measuring HIV
end-points including HIV incidence |
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B.7 |
Alternative microbicide efficacy trials designs |
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| TRACK C Socio-behavioural |
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C.1 |
Acceptability: initiation and use of
various microbicide formulations and delivery mechanisms in different geographic
settings and populations. Discussion of theoretical frameworks to
examine acceptability encouraged |
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C.2 |
Adherence: including development of
adherence-related measures, triangulation of data collection methods
and/or analysis procedures, use of social science theory and/or research
methods to boost adherence within trials - or in future service delivery
settings |
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C.3 |
Rectal Microbicides: prevalence of anal sex in men
and women; acceptability of microbicide gel for rectal use |
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C.4 |
Male Involvement in Microbicide Research: partner
consent for trial participation; male acceptability of microbicides;
influence of trial participation and microbicide use on sexual
partnerships |
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C.5 |
Social Science research on Standards of
Care: participant and/or community research on attitudes towards SOC
levels, research on ethics and informed consent issues |
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C.6 |
Supporting Clinical trials: social science
research on recruitment, informed consent, retention, assessing
adherence, closing out trials |
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C.7 |
Access to Microbicides beyond Clinical Trials: focus
on how providers, product costs and service delivery mechanisms may
influence microbicide accessibility, acceptability and use in a
post-marketing situation. Drawing lessons from other HIV prevention
research studies |
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| Track D Policy, Advocacy and Community |
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D.1 |
Policy |
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- Policies that support microbicide development and research, and
access.
- Involvement of positive people and their role in developing and
implementing policy (and research)
- Standards of prevention, treatment and care for trial
participants – policy issues
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D.2 |
Advocacy: |
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- Microbicides advocacy aimed at a variety of stakeholders—women,
policy makers, trial communities, donors, people with HIV, etc.
- Preparing stakeholders for research results
- Ensuring rapid access to proven microbicide products
- Standards of prevention, treatment and care for trial
participants – advocacy issues
- Mobilising relevant partners (policy makers, donors, agencies,
media etc) to support
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D.3 |
Community: |
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- Community mobilisation, preparedness and involvement – creating
effective partnerships
- Community Advisory Boards
- Defining, understanding and involving the community
- Mobilising communities for microbicides
- Working with the media
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